All About MDMA

Drug Class

Entactogen

Individual Drugs

MDMA, MDA, MDEA, +125 analogs (variants made to mimic the effects of MDMA)

Common Terms

E, Ecstasy, X, Molly, M

Consumption and Standard Dose
  • Pressed pill or capsule. Pills come in various sizes and colours, stamped with different logos. In pressed pill form it is usually sold as “Ecstasy”, and is often sold as a less pure, less expensive form.
  • “Pure MDMA” or just “MDMA” usually comes in a clear capsule and is usually sold as a more pure high at a higher cost. You can determine how much MDMA and other substances are in it by using a pill testing or drug screening test, such as those available through www.dancesafe.org and tripproject.ca.
  • 100-125mg (this varies widely when in pill form, and there maybe no actual MDMA present).
  • Can also be snorted, injected or hooped (placed up the ass). MDMA does not have the numbing qualities of cocaine, and so snorting or hooping it can burn.

The Buzz
  • When swallowed the effects come on within 20 – 40 minutes
  • Waves of exhilaration that peak 60 – 90 minutes after ingestion
  • Increased heart rate, blood pressure, body temperature and pupil dilation
  • Suppression of appetite
  • Increased energy and alertness
  • Euphoric feelings of good-will, empathy, understanding and acceptance of self and others
  • Effects last between 3-5 hours
  • Energy effects may last longer depending on other substances in the pill

Overdose and other negative effects
  • MDMA is notoriously mixed with other substances with a great amount of variation between batches. Overdoses commonly occur when people do not feel effects of a pill, they take and then take a second or third one.
  • In higher doses, and in hot environments like crowded dance floors, you can overheat
  • Overheating can lead to seizures, strokes, heart attacks or difficulty breathing
  • Jaw clenching and teeth grinding can wear down your teeth or create cuts inside your mouth.
  • Temporary short term memory impairment (you forget what’s going on or what conversations you are having).
  • Difficulty obtaining or maintaining an erection.
  • After-effects, or MDMA hangover, can cause depression, agitation, anxiety, panic attacks and paranoia which can last for a few days after use. It takes a few days for your brain to recover and replenish your brain’s balance of serotonin.
  • Continued long-term use can prolong mood-related symptoms, such as depression and anxiety.

Dangerous Drug Combinations
  • Mixing with alcohol deadens the effects of MDMA, and MDMA makes it it hard to gauge how drunk you are. 
  • Mixing with alcohol increases dehydration, which strains kidney and liver functions, and thermoregulation. Most MDMA-related deaths involve mixing alcohol.
  • Mixing with other stimulants increases risk of overheating, dehydration, heart-attack and stroke.
  • Mixing with downers can place strain on your heart.
  • Avoid taking MDMA if you are on antidepressant medication, especially MAOIs, an older type of antidepressant. The two drugs can cause an intense depressive or anxious state. If this happens, seek medical help immediately. If you’re on anti-depressants get medical advice before taking MDMA.
  • Be careful mixing with erectile drugs. If you do mix, take only ½ of each. If you get an erection that lasts more than 4 hours, go to a hospital emergency room.

Sex on MDMA
  • MDMA is cut with other drugs, and thus experience of sex can be mixed.
  • The more actual MDMA is present, the more these feelings will be present:
    • Increased feelings of emotional closeness and empathy
    • Feel in love with someone in a short period of time
    • Feel “cuddly,” sweet and emotionally intimate
    • More physically intense and sensitive
    • Can make sex feel deeper and more meaningful
    • Temporary erectile dysfunction and lessening of sex drive is common
  • The more amphetamine present, the more these feelings will be present:
    • Urgent, lusty, “grindy”, more physical, less emotional

HIV Medications & MDMA
  • All Protease Inhibitors (PIs), as well as Elvitegravir /Cobicistat/TDF/FTC (Stribild) increase the amount of MDMA in your system. This is important to consider, as MDMA puts stress on your heart
  • Idinavir (Crixivan) can increase chance of kidney stones due to dehydration
  • Iopinavir/Ritonavir (Kaltra/Norvir) increases E/MDMA levels 5-10 times. Avoid taking MDMA if you are on these medications
  • MDMA is adultered with other substances, especially PMA/PMMA, mephedrone and methylone.
  • Test your MDMA to know what’s in it. You can order testing kits through TRIP or www.dancesafe.org